Graphical AbstractCephalopods provide a unique model system to investigate how organismal novelties evolve. In article number 1900073, Elena A. Ritschard et al. discuss how co-evolutionary signatures among various genomic characters have contributed to cephalopod organismal novelties and can be used to dissect their functional organization. Cover illustration by Hannah Schmidbaur.

How genomic innovation translates into organismal organization remains largely unanswered. Possessing the largest invertebrate nervous system, in conjunction with many species‐specific organs, coleoid cephalopods (octopuses, squids, cuttlefishes) provide exciting model systems to investigate how organismal novelties evolve. However, dissecting these processes requires novel approaches that enable deeper interrogation of genome evolution. Here, the existence of specific sets of genomic co‐evolutionary signatures between expanded gene families, genome reorganization, and novel genes is posited. It is reasoned that their co‐evolution has contributed to (...) the complex organization of cephalopod nervous systems and the emergence of ecologically unique organs. In the course of reviewing this field, how the first cephalopod genomic studies have begun to shed light on the molecular underpinnings of morphological novelty is illustrated and their impact on directing future research is described. It is argued that the application and evolutionary profiling of evolutionary signatures from these studies will help identify and dissect the organismal principles of cephalopod innovations. By providing specific examples, the implications of this approach both within and beyond cephalopod biology are discussed. (shrink)

The concept of joint action is at the core of numerous diverse research topics, including philosophical explorations of social action, studies of human dialogue, human-computer interaction, computer-supported collaborative work, multiagent systems, distributed artificial intelligence, distributed simulation, and contract law. It is therefore remarkable that so central a concept has received so little detailed analysis, in comparison with studies of individuals. However, in recent years, the study of joint action has begun to undergo more intense scrutiny, primarily from philosophers and researchers (...) in artificial intelligence. These two disciplines often address similar topics but with different motivations, methodologies, tools, and criteria for success. Although this paper is inspired by philosophical work, it is squarely motivated by the concerns of building intelligent systems that are capable of collaborative behavior, either with a user, or with other such systems. Still, we hope that the paper sheds light on philosophical issues, and treats the subject of joint action at a sufficiently precise level to be illuminating of problems that any philosophical account needs to confront. (shrink)

Professional, Ethical, Legal, and Educational Lessons in Medicine: A Problem Based Approach provides a comprehensive review of the complex and challenging field of professional medical practice. Its problem-based format incorporates a vast pool of practical, board-exam-style multiple-choice questions for self-assessment, and is an ideal resource for exam preparation as well as ongoing clinical education among trainees and clinicians The practice of medicine is not only about clinical care of patients. Physicians must navigate ethical conundrums, legal pitfalls, and quality improvement issues (...) while maintaining scrupulous professionalism and being exemplary educators. This volume addresses common issues in the realm of professional medical practice not typically covered in other texts. Each of the 73 chapters presents a problem-based case that branches out into an oral board examination type stem questions. A discussion section with brief review articles summarizes the most recent literature. Multiple-choice questions with answers allows for comprehensive self-assessment or interactive group quizzes. This book will appeal to medical and allied health professionals in all specialties of medicine. It is an excellent and hands-on reference for the related but diverse domains associated with professional healthcare practice by students, physicians, and other healthcare providers compacted into one volume. (shrink)

The federal government is funding a sea change in health care by investing in interventions targeting social determinants of health, which are significant contributors to illness and health inequity. This funding power has encouraged states, professional and accreditation organizations, health care entities, and providers to focus heavily on social determinants. We examine how this shift in focus affects clinical practice in the fields of oncology and emergency medicine, and highlight potential areas of reform.

Collection of studies on a leading moral philosopher and his work, or dedicated to him.

Biologists, historians, lawyers, art historians, and literary critics all voice arguments in the critical dialogue about what constitutes evidence in research and scholarship. They examine not only the constitution and "blurring" of disciplinary boundaries, but also the configuration of the fact-evidence distinctions made in different disciplines and historical moments the relative function of such concepts as "self-evidence," "experience," "test," "testimony," and "textuality" in varied academic discourses and the way "rules of evidence" are themselves products of historical developments. The essays and (...) rejoinders are by Terry Castle, Lorraine Daston, Carlo Ginzburg, Ian Hacking, Mark Kelman, R. C. Lewontin, Pierre Vidal-Naquet, Mary Poovey, Donald Preziosi, Simon Schaffer, Joan W. Scott, Eve Kosofsky Sedgwick, and Barbara Herrnstein Smith. The critical responses are by Lauren Berlant, James Chandler, Jean Comaroff, Arnold I. Davidson, Harry D. harootunian, Elizabeth Helsinger, Thomas C. Holt, Francoise Meltzer, Robert J. Richards, Lawrence Rothfield, Joel Snyder, Cass R. Sunstein, and William Wimsatt. (shrink)

This second installment from the author's book-length study of Ralph Wendell Burhoe's life and thought details the background of the establishing of the Institute on Religion in an Age of Science in 1955 and its intellectual rationale. A group of clergy from the Coming Great Church Conference and scientists who were members of the Committee on Science and Values of the American Academy of Arts and Sciences came together to form the new Institute on Star Island, off the coast of (...) Portsmouth, New Hampshire. From the beginning, with the guidance of Burhoe, the chief concern of these scientists and clergy was the need to regenerate a contemporary civilization that was on the brink of danger due to its inability to discipline its own burgeoning scientific and technological prowess. Revitalizing religion was deemed essential to this regeneration of society. Since religion is largely destabilized by science, the major task is to emphasize how contemporary scientific understandings support religious wisdom and accentuate its importance. This task is to be accomplished through a science-based theology which reformulates religious wisdom for a culture that accepts science as the most reliable form of knowledge. This rationale for IRAS also articulates the program to which Burhoe committed himself. (shrink)

This fifth and final installment from the author's book‐length study of Ralph Wendell Burhoe's life and thought covers the period 1966–1987, and it concludes with a summary of his thought. Zygon: Journal of Religion and Science began publication in March 1966, the same year in which the Center for Advanced Study in Theology and the Sciences (CASTS) was founded. Both the journal and the center were made possible by Meadville/Lombard Theological School. After a brief period of flourishing, CASTS was succeeded (...) in 1972 by the Center for Advanced Study in Religion and Science (CASIRAS). Burhoe married Calla Butler in 1969, two years after his first wife, Frances, had died. He retired from Mead‐ville in 1974. The Templeton Prize for Progress in Religion was awarded to Burhoe in 1980. His thought is summarized under the topics of values, thermodynamics, the evolution of religion, the concept of soul, God, enculturation and freedom, and the Lord of History. (shrink)

This fifth and final installment from the author's book‐length study of Ralph Wendell Burhoe's life and thought covers the period 1966–1987, and it concludes with a summary of his thought. Zygon: Journal of Religion and Science began publication in March 1966, the same year in which the Center for Advanced Study in Theology and the Sciences (CASTS) was founded. Both the journal and the center were made possible by Meadville/Lombard Theological School. After a brief period of flourishing, CASTS was succeeded (...) in 1972 by the Center for Advanced Study in Religion and Science (CASIRAS). Burhoe married Calla Butler in 1969, two years after his first wife, Frances, had died. He retired from Mead‐ville in 1974. The Templeton Prize for Progress in Religion was awarded to Burhoe in 1980. His thought is summarized under the topics of values, thermodynamics, the evolution of religion, the concept of soul, God, enculturation and freedom, and the Lord of History. (shrink)

Még 2013 májusában került sor arra a Metafora című nyelvészeti és filozófiai workshopra, amelynek a keretein belül elhangzottak a jelen kötetben helyet kapott tanulmányok alapját képező, az Erasmus Kollégium nyelvfilozófiai kutatócsoportjának tagjai által jegyzett előadások. Ezeknek, s így a mostani összeállításnak is kiemelt témája a relevanciaelmélet, amellyel (pontosabban annak metaforafelfogásával) részletesen foglalkozik a bevezető dolgozat, illetve az azt követő három írás. Ezek közül az elsőben Pete Krisztián a teória klasszikus vonulatát állítja párhuzamba az átdolgozott, továbbfejlesztett változatokkal, majd Zvolenszky Zsófia - (...) részben ehhez kapcsolódva - a konvencionális és költői metaforák témáját illetően kritikával illeti a modern megközelítést. Kuti Judit a Sperber-Wilson- és a Harald Weinrich-féle metaforaelméletet hasonlítja össze. A folytatásban olyanok metaforaleméleteivel ismerkedhetünk meg, mint Donald Davidson és Paul Ricoeur; Kálmán László egy hagyományos irányzatból kinövő, mégis új nyelvfelfogást és metaforaelemzést mutat be; Kiss Angelika és Jellinek Sára egy-egy nyelvhasználati jelenséget és metaforikus beszédmódot mutat be (a japán és koreai nyelv, és a humor nyelvfilozófiai vonatkozásai kapcsán); Nemesi Attila László a filmes és mozgóképes trópusokról, s azok csoportosításáról ír; Molnár Cecília Sarolta pedig a mai modern dalszövegek metaforakészletét elemzi. A mutatóval záruló kiadvány nyelvészeti szakgyűjteményekbe javasolható beszerzésre. (shrink)

Although Dirār b. ʿAmr is the most important mutakallim of the second century, he is unfortunately one of the unjustified names in the history of kalām. Dirâr is a mutakallim whose name is rarely mentioned in theological publications published in both Turkish and foreign languages until recently, and his importance and position are still not noticed. As a matter of fact, Josef van Ess and W. Montgomery Watt, who are famous orientalists, discovered this tragic fact and tried to make up (...) for this deficiency to some extent with their studies. Dirâr wrote a refutation of Aristotle's theory of substance and accident, opened a new way with his understanding of existence based on accidents and led Ash'ari with the theory of kasb and Ebu'l-Huzayl al-‘Allaf with his kalām accumulation. Undoubtedly, one of the things that makes Dirār important is that he had views that went beyond his time and caused him to contradict his contemporaries as early as the second century in terms of the history of Islamic thought. Considering the list of works that have not survived, except for one, in such a period when the mainstream sects were not yet formed and they were on the eve of their formation, Dirār was generally in a critical dialogue with the Islamic and non-Islamic movements he encountered and knew. For this reason, it is almost impossible to place him in any religious sect mentioned in his period. Because he often preferred to follow his own ideas rather than the opinions of others on many issues. Naturally, this makes it difficult to place Dirār in a certain school and frees him from all kinds of bonds. Yes, in the sources we come across many allegations, accusations and slanders that Dirār is a Cahmi/Jabri, he is a Mu‘tazili, he is an innovator with malignant ideas, he is an infidel to put a bounty on his head. Understanding the reasons for these depends on getting to know Dirār, understanding his ideas, and determining his position. If we say in the context of our study, the position of Dirār is actually a state of non-position, and we think that the concept that best expresses this situation in a new interpretation is "nawābit". In the light of our analysis, we see that, with the exception of a name, nawābit is used as a concept with a negative content and connotation in both theology and philosophy. The exceptional person is the famous philosopher Ibn Bājja (Avempace) from Andalusia, the contemporary of Ibn Rushd (Averroes). While Mu‘tazili mutakallims use nawābit to humiliate groups such as Ahl-i hadith and Hashviyye, which adopt the narration-oriented line that puts reason and acumen to the second place, Al-Fārābī also uses the fault types and the sick characters in his virtuous city that he has constructed to describe. Ibn Bājja, on the other hand, considers the people called nawābit within his project to be equivalent to the "mutawahhid" (alone human) whose "precaution" he aims; this usage which corresponds with the context of the concept in the study. Because, in our study, nawābit is not considered as an identity, but as a representation of a character. (shrink)